Unit 5    Molecular Genetics  Study Guide

ü     Be able to describe & explain the experiments of the following scientists:
Frederick Griffith
Erwin Chargraff
Alfred Hershey
Martha Chase
Watson & Crick
Meselson & Stahl
Beadle & Tatum
“Dolly” experiment 

ü     Know how DNA replicates including steps & the enzymes involved, energy required, nucleotides, leading & lagging strands, proofreading

ü     Be able to describe the ultrastructure of each component of the DNA & RNA molecules

ü     Know the steps of transcription, enzymes involved, etc

ü     Know the steps of translation, enzymes involved, etc.

ü     Be able to describe the structure & function of free and bound ribosomes

ü     Know the processing steps of newly made mRNA

ü     Know the types of mutations and their effects

ü     Know viral structure, reproduction, host recognition, viral genome, etc

ü     Be able to describe the prokaryotic genome, mechanisms for genetic recombination, & defenses against phages

ü     Differentiate between hetero- & euchromatin

ü     Know the function and use of restriction enzymes

ü     Be able to describe genomic differentiation